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Acebrophylline + Acetylcysteine is a combination of two medicines : Acebrophylline and Acetylcysteine. Acebrophylline is a mucolytic and bronchodilator. It works by relaxing the muscles of the airways and also thins and loosens mucus, making it easier to breathe. Acetylcysteine is a mucolytic medication. It thins and loosens mucus (phlegm) making it easier to cough out.